Lunar Occultation
An important international astronomical program which concerns the timing determination of occulted and divulged stars from the lunar disk. The accomplished lunar occultation observations are sent to the International Occultation Timing Association (IOTA), which has the international supervision of the program.

Stellar Photoelectric Photometry (PEP)
The Observatory of Larissa has been participating for years at the international AAVSO Photoelectric Photometry (PEP) observing program whose purpose is to study a group of 80 specially selected macro-periodic variable stars with small wavewidth. We make experimental observations with photoelectric and ocular methods in order to determine the minimum periods of the special category of variable of Algol type (eclipsing binary stars). We also participate in the concurrent program of photoelectric photometric observation of the star IM PEG. The purpose of the earthy and satellite observations is to accomplish a sophisticated examination of certain aspects of the theory of relativity.

Geophysical program
a) We monitor the seismic activity of the wider area of Thessaly with seismograph of the Observatory. The recorded earthquakes, after their calculation and archiving in special publications, are then sent to the Geophysical Laboratory of the Aristotle University of Thessalonica and the Geodynamic Institute of Athens.

Educational program
The Observatory of Larissa is visited by students of all levels all year round. In the specially adapted and equipped with modern projection instruments room at the second floor, we provide lectures and projections of films or videos of astronomic interest. Also, on all Thursday afternoons admission to the Observatory is free for all members of the public.